MLB Best Bets Today: Expert Predictions & Picks for Astros vs Royals, Cubs vs Giants, and More on Saturday, June 13

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We have a full 15-game slate today, starting early with Cardinals vs Twins at 2:10 PM ET at Target Field on MLB.TV, including Astros vs Royals at 7:10 PM ET at Kauffman Stadium on MLB.TV, and closing with Cubs vs Giants 10:05 PM ET at Oracle Field on MLB.TV.

Our experts have analyzed the matchups and found great options for Saturday, June 13.

Below are 4 expert MLB best bets today.

The team logos in the table below represent each matchup our MLB betting staff is targeting from today's slate of games. Click on the team logos for any of the matchups below to navigate to a specific bet discussed in this article.

This season, both these teams are tied for 11th in runs scored per game at 4.5.

That said, the Twins have shown promising metrics against Matthew Liberatore.

In 17 combined plate appearances against the left-hander, the current Minnesota roster owns a .435 xBA and a .656 xSLG.

At a near pick ‘em, the Twins are the side to back in this matchup.

Yoshinobu Yamamoto is coming off a season-high eight innings of two-hit ball against the Angels, surrendering a single run, but only striking out four, just one start after setting his season high of 10 strikeouts against the Phillies.

Since a four-game stretch where Yamamoto allowed at least three runs in each start (15 over 24 innings total), he’s allowed just three runs in 27.1 innings with a 19.8 K-BB%, 30.4 HardHit%, and a single barrel.

His 2.68 ERA is a bit below estimates ranging from 3.13 dERA to 3.42 FIP, though I project him to be most aligned with his 3.23 xFIP.

The .240 BABIP isn’t much lower than last year (.243), but probably increases a bit going forward.

Still, Yamamoto is clearly the superior starting pitcher in this game, around three-quarters of a run ahead of Sean Burke, whose 3.88 ERA is within one-third of a run of all indicators except for a 4.44 dERA.

On top of that, the Dodgers' offense puts up video-game numbers.

Yet, consider that the White Sox haven’t been bad in comparison

The Dodgers still claim that edge, along with approximately two-thirds of a run on bullpen estimators over the last 30 days, while BARTOLO sees a 14-team gap between the relief corps of the two teams.

The one area where the White Sox compete with the Dodgers is defense, where they have a projected +2 FRV edge.

I project the Dodgers as a healthy favorite, just not this healthy.

I don't see the skill sets this far apart and have it closer to -150 than the current number, where you can get the home team at +176 (FanDuel).

Dodger edges are more moderate than monstrous, with a good White Sox squad clawing just a bit back with defense and home field.

It’s not a comfortable bet against a hot pitcher, but as I’m fond of saying, everything has a price, and the White Sox appear to have hit theirs.

I expect the Royals to have a massive pitching edge in this matchup, largely due to the recent form of 26-year-old lefty Noah Cameron.

In addition to Burrows’ struggles, Cameron is coming off a phenomenal 2025 campaign and appears to be reverting back to his elite form despite opening 2026 with a few rocky starts.

Over his last four outings, the Royals' lefty has allowed just four earned runs across 24 innings while striking out 27 hitters.

After posting remarkable splits as a rookie in 2025, finishing with a 2.99 ERA and a 1.10 WHIP, Cameron began his second season in the majors with a case of the “sophomore slump.”

Since then, Noah has reverted to his elite 2025 form on the mound and has quickly re-established himself as one of the best young starters in baseball.

While the Royals have struggled as a team to begin the 2026 season, I love them on Saturday night, as I expect Cameron to dazzle in another impressive outing.

I project some value on the Cubs in this matchup.

While the consensus line sits around -125, I project the Cubs ML at -157, representing a 5% edge against the market.

As a reminder, you can see all of my MLB game projections with an Action PRO Subscription.

Find his projected lines every day on the PRO Projections tab.

Additionally, you can get access to my new PRO baseball betting tool, BARTOLO, with a PRO subscription.

The full version drops next week, but here's a sneak peek at the kind of information available in the tool:

I would bet the Cubs ML at -145 or better.

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